Course content
1
Opening
Opening of the 2025 Summer School of Reproductologist (Paris, 02.07.2025) — a scientific symposium following ESHRE 2025. The program focuses on what influences implantation, recurrent implantation failure and current approaches to ART patient management.
5:08
2
Nick Macklon
Why euploid embryos fail to implant?
The failed implantation of a euploid blastocyst is a clinical problem that bridges two schools of thought: «embryo-centric» and «endometrium-centric». The concept of the endometrium as a biosensor explains why, with embryos of average quality, endometrial receptivity and selectivity determine the outcome. A review of current evidence and the clinical grading of RIF (recurrent implantation failure) per the ESHRE 2023 consensus.
40:23
3
Paul Pirtea
Recurrent implantation failure, reality or a statistical mirage?
Is recurrent implantation failure a distinct clinical entity — or a statistical artefact created by the absence of a unified definition? Data on cumulative pregnancy and live birth rates across serial euploid embryo transfers, plus consensus algorithms (ESHRE 2023, Lugano 2023) for diagnosis, work-up and management.
30:38
4
Elena Labarta
Personalized luteal phase support
Luteal phase support based on serum progesterone monitoring: why standard vaginal therapy fails to reach the protective level in a subset of patients on the hormone replacement cycle, how to define the threshold value on transfer day, and when a change in the route of administration is indicated. Arguments for moving toward natural and modified natural FET cycles.
26:45
5
Christophe Blockeel
Overweight, obesity and reproductive outcomes
The impact of overweight and obesity on reproductive outcomes: ovarian response, embryo quality, endometrial receptivity and obstetric consequences. Why BMI alone is insufficient for clinical decisions — and how body composition assessment (bioelectrical impedance, indirect calorimetry, food diary) makes pre-cycle workup truly individualized.
31:37
6
Carlo Alviggi
Adenomyosis and infertility
Adenomyosis and infertility: phenotype classification (internal/junctional zone, intermediate, external), current diagnostic approaches (MRI, ultrasound per MUSA criteria, hysteroscopy) and the evidence base regarding impact on ART outcomes. Management algorithm in clinically significant adenomyosis: cycle segmentation, accumulation of euploid blastocysts, GnRH agonist pretreatment before FET, selective hysteroscopic resection.
32:50
7
Baris Ata
Thin endometrium — should embryo transfer be cancelled?
Thin endometrium remains one of the most debated topics in reproductive medicine. Is it justified to cancel transfer at a thickness of <7 mm? Analysis of the evidence base — from classical work of the late 1980s to current multicentre cohorts (~30,000 cycles) — shows that with proper work-up (exclusion of intracavitary pathology and premature progesterone exposure), the live birth rate at thickness <7 mm remains in the 42–47% range.
27:33
