Reproductive healthLecture
Protocols and Decisions: Trigger Selection and Oocyte Quality
The trigger is one small injection at the end of stimulation — and most of the cycle outcome rides on it. A practical walk through trigger choice (HCG, agonist, dual, double), the Vienna consensus 80-95% oocyte yield ratio, and what each trigger does to oocyte maturation in real protocols.
Audio: UASubtitles: EN · UA · RU50 min
Halyna Strelko
Professor, MD, PhD, DSc
Professor and Doctor of Medical Sciences, Medical Director and co-founder of the IVMED clinic in Kyiv and a specialist in reproductive medicine.
Ukraine
What was shown
The trigger is one small injection at the end of stimulation — and most of the cycle outcome rides on it. The talk walks through HCG, GnRH agonist, dual and double trigger strategies, the Vienna consensus 80-95% oocyte yield target, and the practical decisions that connect trigger choice to oocyte maturation in real protocols.
Key findings
HCG remains the workhorse trigger but extends LH-like activity over 6-7 days, driving the progesterone surge in fresh cycles. Agonist trigger gives a much shorter LH peak (24-28 hours) and a steep luteal-phase drop — needs rescue if transferring fresh. Dual trigger (agonist + HCG) recovers oocyte maturation in cases with low yield-per-follicle ratio. The Vienna consensus oocyte-yield target of 80-95% of antral follicles is a usable lab quality marker.
